DSRF UK grew out of an awareness of the connection between lack of research and the danger of premature acceptance of health conditions that can come with Down syndrome. In an age of rapid medical advances, we firmly believe that the necessary high quality research that underpins all scientific progress is also needed for people with Down syndrome. 

We have a strong track record of funding and promoting world-class pioneering research related to Trisomy 21. To date we have funded and supported a broad range of research projects involving these areas and more: Sleep, Menstrual Health, Language, Attention, Memory, and Photobiomodulation, Epigenetics, Metabolism, Obesity, Alzheimers, Hearing Loss, Probiotics, Supplementation, and Nutritional Intervention.

We are also involved in advocacy and human rights, and have been instrumental along with others in the passing of the Down Syndrome Act (2022) which mandated the publication of statutory guidance on the specific needs of people with DS. 

Despite being the most common chromosomal condition and affecting 1 in 1,000 births, Down syndrome receives the least funding of all congenital conditions. Legacies can play a vital role in bridging this enormous gap, allowing us to accelerate advances in knowledge and improvements in treatment, bringing about a better quality of life for any individual with Down syndrome.